1.2 Gene regulation

The process by which genes are controlled. When they are turned on or off, how much to make. Often has a cascading effect.

1.2.1 Transcriptional regulation

Control output of transcripts before transcription occurs.

Transcription factors Transcription factors. Source: https://www.discoveryandinnovation.com/BIOL202/notes/images/overview.jpg Epigenetic (histone) modifications Histone modifications. Source: https://s3-us-west-2.amazonaws.com/courses-images/wp-content/uploads/sites/1087/2016/12/12233132/Figure_16_03_03.jpg

1.2.2 Post-transcriptional regulation

Control what happens to transcripts after they are made.

Splicing mRNA Splicing. Source: https://www.thelancet.com/cms/attachment/4dc4ebd6-928c-461e-8d88-77670862487a/gr2_lrg.jpg

non-coding RNAs (ncRNAs) ncRNA. Source: http://chenyuan.date/images/ncRNA_1.jpg